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IL-13 and Epidermal Growth Factor Receptor Have Critical but Distinct Roles in Epithelial Cell Mucin Production

Overproduction of mucus is a central feature of asthma. The cytokine, IL-13, epidermal growth factor receptor (EGFR), and transcription factor, FOXA2, have each been implicated in mucus production, but the mechanistic relationships between these molecules are not yet well understood. To address this...

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Main Authors: Zhen, Guohua, Park, Sung Woo, Nguyenvu, Louis T., Rodriguez, Madeleine W., Barbeau, Rebecca, Paquet, Agnes C., Erle, David J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Thoracic Society 2007
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899314/
https://ncbi.nlm.nih.gov/pubmed/16980555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2006-0180OC
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