IL-13 and Epidermal Growth Factor Receptor Have Critical but Distinct Roles in Epithelial Cell Mucin Production

Overproduction of mucus is a central feature of asthma. The cytokine, IL-13, epidermal growth factor receptor (EGFR), and transcription factor, FOXA2, have each been implicated in mucus production, but the mechanistic relationships between these molecules are not yet well understood. To address this...

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Hlavní autoři: Zhen, Guohua, Park, Sung Woo, Nguyenvu, Louis T., Rodriguez, Madeleine W., Barbeau, Rebecca, Paquet, Agnes C., Erle, David J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2007
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899314/
https://ncbi.nlm.nih.gov/pubmed/16980555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2006-0180OC
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