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IL-13 and Epidermal Growth Factor Receptor Have Critical but Distinct Roles in Epithelial Cell Mucin Production

Overproduction of mucus is a central feature of asthma. The cytokine, IL-13, epidermal growth factor receptor (EGFR), and transcription factor, FOXA2, have each been implicated in mucus production, but the mechanistic relationships between these molecules are not yet well understood. To address this...

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Bibliografiske detaljer
Main Authors: Zhen, Guohua, Park, Sung Woo, Nguyenvu, Louis T., Rodriguez, Madeleine W., Barbeau, Rebecca, Paquet, Agnes C., Erle, David J.
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899314/
https://ncbi.nlm.nih.gov/pubmed/16980555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2006-0180OC
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