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AGR2 Is Induced in Asthma and Promotes Allergen-Induced Mucin Overproduction

Mucins are gel-forming proteins that are responsible for the characteristic viscoelastic properties of mucus. Mucin overproduction is a hallmark of asthma, but the cellular requirements for airway mucin production are poorly understood. The endoplasmic reticulum (ER) protein anterior gradient homolo...

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Autors principals: Schroeder, Bradley W., Verhaeghe, Catherine, Park, Sung-Woo, Nguyenvu, Louis T., Huang, Xiaozhu, Zhen, Guohua, Erle, David J.
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423459/
https://ncbi.nlm.nih.gov/pubmed/22403803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2011-0421OC
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