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The Epithelial Anion Transporter Pendrin Is Induced by Allergy and Rhinovirus Infection, Regulates Airway Surface Liquid, and Increases Airway Reactivity and Inflammation in an Asthma Model

Asthma exacerbations can be triggered by viral infections or allergens. The Th2 cytokines IL-13 and IL-4 are produced during allergic responses and cause increases in airway epithelial cell mucus, electrolyte and water secretion into the airway surface liquid (ASL). Since ASL dehydration can cause a...

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Hlavní autoři:	Nakagami, Yasuhiro, Favoreto, Silvio, Zhen, Guohua, Park, Sung-Woo, Nguyenvu, Louis T., Kuperman, Douglas A., Dolganov, Gregory M., Huang, Xiaozhu, Boushey, Homer A., Avila, Pedro C., Erle, David J.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	2008
Témata:	Article
On-line přístup:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2491716/ https://ncbi.nlm.nih.gov/pubmed/18641360
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo otaguje tento záznam!

The Epithelial Anion Transporter Pendrin Is Induced by Allergy and Rhinovirus Infection, Regulates Airway Surface Liquid, and Increases Airway Reactivity and Inflammation in an Asthma Model

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