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Thick airway surface liquid volume and weak mucin expression in pendrin-deficient human airway epithelia

Pendrin is an anion exchanger whose mutations are known to cause hearing loss. However, recent data support the linkage between pendrin expression and airway diseases, such as asthma. To evaluate the role of pendrin in the regulation of the airway surface liquid (ASL) volume and mucin expression, we...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Lee, Hyun Jae, Yoo, Jee Eun, Namkung, Wan, Cho, Hyung-Ju, Kim, Kyubo, Kang, Joo Wan, Yoon, Joo-Heon, Choi, Jae Young
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562566/
https://ncbi.nlm.nih.gov/pubmed/26243215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12480
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