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Soluble Mediators, Not Cilia, Determine Airway Surface Liquid Volume in Normal and Cystic Fibrosis Superficial Airway Epithelia

A key aspect of the lung's innate defense system is the ability of the superficial epithelium to regulate airway surface liquid (ASL) volume to maintain a 7-μm periciliary liquid layer (PCL), which is required for cilia to beat and produce mucus flow. The mechanisms whereby airway epithelia reg...

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Detalles Bibliográficos
Main Authors: Tarran, Robert, Trout, Laura, Donaldson, Scott H., Boucher, Richard C.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151517/
https://ncbi.nlm.nih.gov/pubmed/16636206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200509468
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