Mucin Production and Hydration Responses to Mucopurulent Materials in Normal versus Cystic Fibrosis Airway Epithelia

Rationale: Cystic fibrosis (CF) airways disease produces a mucoobstructive lung phenotype characterized by airways mucus plugging, epithelial mucous cell metaplasia/hyperplasia, chronic infection, and inflammation. Simultaneous biochemical and functional in vivo studies of mucin synthesis and secret...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Abdullah, Lubna H., Coakley, Raymond, Webster, Megan J., Zhu, Yunxiang, Tarran, Robert, Radicioni, Giorgia, Kesimer, Mehmet, Boucher, Richard C., Davis, C. William, Ribeiro, Carla M. P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821906/
https://ncbi.nlm.nih.gov/pubmed/29099608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201706-1139OC
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