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Cystic fibrosis airway secretions exhibit mucin hyperconcentration and increased osmotic pressure
The pathogenesis of mucoinfective lung disease in cystic fibrosis (CF) patients likely involves poor mucus clearance. A recent model of mucus clearance predicts that mucus flow depends on the relative mucin concentration of the mucus layer compared with that of the periciliary layer; however, mucin...
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| Hauptverfasser: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4072023/ https://ncbi.nlm.nih.gov/pubmed/24892808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI73469 |
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