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Periciliary Brush Promotes the Lung Health by Separating the Mucus Layer from Airway Epithelia

Mucus clearance is the primary defense mechanism that protects airways from inhaled infectious and toxic agents. In the current Gel-on-Liquid mucus clearance model mucus gel is propelled on top of a “watery” periciliary layer surrounding the cilia. However, this model fails to explain the formation...

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Detalhes bibliográficos
Main Authors: Button, Brian, Cai, Li-Heng, Ehre, Camille, Kesimer, Mehmet, Hill, David B., Sheehan, John K., Boucher, Richard C., Rubinstein, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633213/
https://ncbi.nlm.nih.gov/pubmed/22923574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1223012
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