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IL-13 and Epidermal Growth Factor Receptor Have Critical but Distinct Roles in Epithelial Cell Mucin Production

Overproduction of mucus is a central feature of asthma. The cytokine, IL-13, epidermal growth factor receptor (EGFR), and transcription factor, FOXA2, have each been implicated in mucus production, but the mechanistic relationships between these molecules are not yet well understood. To address this...

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Main Authors: Zhen, Guohua, Park, Sung Woo, Nguyenvu, Louis T., Rodriguez, Madeleine W., Barbeau, Rebecca, Paquet, Agnes C., Erle, David J.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Thoracic Society 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899314/
https://ncbi.nlm.nih.gov/pubmed/16980555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2006-0180OC
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