Epinephrine Activation of the β(2)-Adrenoceptor Is Required for IL-13-Induced Mucin Production in Human Bronchial Epithelial Cells

Mucus hypersecretion by airway epithelium is a hallmark of inflammation in allergic asthma and results in airway narrowing and obstruction. Others have shown that administration a T(H)2 cytokine, IL-13 is sufficient to cause mucus hypersecretion in vivo and in vitro. Asthma therapy often utilizes β(...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Al-Sawalha, Nour, Pokkunuri, Indira, Omoluabi, Ozozoma, Kim, Hosu, Thanawala, Vaidehi J., Hernandez, Adrian, Bond, Richard A., Knoll, Brian J.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498766/
https://ncbi.nlm.nih.gov/pubmed/26161982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132559
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