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IL-13 induces a bronchial epithelial phenotype that is profibrotic
BACKGROUND: Inflammatory cytokines (e.g. IL-13) and mechanical perturbations (e.g. scrape injury) to the epithelium release profibrotic factors such as TGF-β(2), which may, in turn, stimulate subepithelial fibrosis in asthma. We hypothesized that prolonged IL-13 exposure creates a plastic epithelial...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2292179/ https://ncbi.nlm.nih.gov/pubmed/18348727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-9-27 |
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