GM-CSF Regulates a PU.1-Dependent Transcriptional Program Determining the Pulmonary Response to LPS

Alveolar macrophages (AMs) normally respond to lipopolysaccharide (LPS) by activating Toll-like receptor (TLR)-4 signaling, a mechanism critical to lung host defense against gram-negative bacteria such as Pseudomonas aeruginosa. Because granulocyte macrophage colony-stimulating factor (GM-CSF)–defic...

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Detalhes bibliográficos
Main Authors: Berclaz, Pierre-Yves, Carey, Brenna, Fillipi, Marie-Dominique, Wernke-Dollries, Kara, Geraci, Nick, Cush, Stephanie, Richardson, Terry, Kitzmiller, Joe, O'Connor, Michael, Hermoyian, Christina, Korfhagen, Thomas, Whitsett, Jeffrey A., Trapnell, Bruce C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899305/
https://ncbi.nlm.nih.gov/pubmed/16917076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2006-0174OC
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