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Pulmonary alveolar proteinosis, a primary immunodeficiency of impaired GM-CSF stimulation of macrophages

Pulmonary alveolar proteinosis (PAP) is a rare syndrome characterized by accumulation of pulmonary surfactant, respiratory insufficiency, and increased infections. It occurs in various clinical settings that disrupt surfactant catabolism in alveolar macrophages, including a relatively more common au...

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Detalhes bibliográficos
Main Authors: Trapnell, Bruce C., Carey, Brenna C., Uchida, Kanji, Suzuki, Takuji
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779868/
https://ncbi.nlm.nih.gov/pubmed/19796925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2009.09.004
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