Keratinocyte Growth Factor Augments Pulmonary Innate Immunity through Epithelium-driven, GM-CSF-dependent Paracrine Activation of Alveolar Macrophages

Keratinocyte growth factor (KGF) is an epithelial mitogen that has been reported to protect the lungs from a variety of insults. In this study, we tested the hypothesis that KGF augments pulmonary host defense. We found that a single dose of intrapulmonary KGF enhanced the clearance of Escherichia c...

Full description

Saved in:
Bibliographic Details
Main Authors: Wu, Huixing, Suzuki, Takuji, Carey, Brenna, Trapnell, Bruce C., McCormack, Francis X.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083236/
https://ncbi.nlm.nih.gov/pubmed/21343299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.182170
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items