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GM-CSF-dependent peritoneal macrophage responses determine survival in experimentally induced peritonitis and sepsis in mice
GM-CSF plays a critical role in innate immunity by stimulating the differentiation of tissue macrophages via the transcription factor PU.1. Previous studies showed that GM-CSF deficient (GM-CSF(−/−)) mice had susceptibility to and impaired clearance of group B streptococcal bacteria by macrophages....
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2743401/ https://ncbi.nlm.nih.gov/pubmed/18277945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e3181673543 |
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