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The in vivo antiviral activity of interleukin-12 is mediated by gamma interferon.

The injection of 20 ng of mouse interleukin-12 (IL-12) protects mice from a lethal infection with encephalomyocarditis virus. In vitro, an anti-gamma interferon (anti-IFN-gamma) monoclonal antibody but not an anti-IL-12 monoclonal antibody neutralizes the antiviral activity present in the supernatan...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ozmen, L, Aguet, M, Trinchieri, G, Garotta, G
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1995
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC189771/
https://ncbi.nlm.nih.gov/pubmed/7494339
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