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The antiviral state induced by alpha interferon and gamma interferon requires transcriptionally active Stat1 protein.

Both of the latent transcription factors activated by alpha interferon or gamma interferon contain the Stat1 protein. The role of Stat1 in virus interference mediated by interferons was directly examined by using cultured cells expressing Stat1 protein and its variants. In the absence of Stat1, no a...

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Библиографические подробности
Главные авторы: Horvath, C M, Darnell, J E
Формат: Artigo
Язык:Inglês
Опубликовано: 1996
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC189860/
https://ncbi.nlm.nih.gov/pubmed/8523587
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