High-frequency mutagenesis of human cells and characterization of a mutant unresponsive to both alpha and gamma interferons.

2fTGH is a human cell line containing the selectable marker guanine phosphoribosyltransferase regulated by alpha interferon (IFN-alpha). Two IFN-alpha-unresponsive mutants were isolated previously at a low frequency (ca. 10(-8)) by selecting mutagenized 2fTGH cells in selective medium containing 6-t...

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Hlavní autoři: McKendry, R, John, J, Flavell, D, Müller, M, Kerr, I M, Stark, G R
Médium: Artigo
Jazyk:Inglês
Vydáno: 1991
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC53154/
https://ncbi.nlm.nih.gov/pubmed/1837150
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