High-frequency mutagenesis of human cells and characterization of a mutant unresponsive to both alpha and gamma interferons.

2fTGH is a human cell line containing the selectable marker guanine phosphoribosyltransferase regulated by alpha interferon (IFN-alpha). Two IFN-alpha-unresponsive mutants were isolated previously at a low frequency (ca. 10(-8)) by selecting mutagenized 2fTGH cells in selective medium containing 6-t...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	McKendry, R, John, J, Flavell, D, Müller, M, Kerr, I M, Stark, G R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53154/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1837150/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.24.11455
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