Carregant...

Impaired Antiviral Response and Alpha/Beta Interferon Induction in Mice Lacking Beta Interferon

We have generated mice lacking the gene for beta interferon and report that they are highly susceptible to vaccinia virus infection. Furthermore, in cultured embryo fibroblasts, viral induction of alpha interferon and of 2-5A synthetase genes is impaired. We also show that beta interferon does not p...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Deonarain, Raj, Alcamí, Antonio, Alexiou, Maria, Dallman, Margaret J., Gewert, Dirk R., Porter, Andrew C. G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC111842/
https://ncbi.nlm.nih.gov/pubmed/10708458
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!