Effect of alpha interferon (IFN-alpha) on 2'-5' oligoadenylate synthetase activity in peripheral blood mononuclear cells of patients with chronic hepatitis C: relationship to the antiviral effect of IFN-alpha.

Alpha interferon (IFN-alpha) is, to date, the only treatment with proven efficacy in patients with chronic hepatitis C. However, less than 15% of the patients have a sustained response to IFN-alpha. Interferon acts through the induction of various cellular enzymes. Among them, the 2'-5' ol...

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Detalhes bibliográficos
Main Authors: Pawlotsky, J M, Hovanessian, A G, Roudot-Thoraval, F, Robert, N, Bouvier, M, Babany, G, Duval, J, Dhumeaux, D
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC163109/
https://ncbi.nlm.nih.gov/pubmed/8834873
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