Impaired Antiviral Response and Alpha/Beta Interferon Induction in Mice Lacking Beta Interferon

We have generated mice lacking the gene for beta interferon and report that they are highly susceptible to vaccinia virus infection. Furthermore, in cultured embryo fibroblasts, viral induction of alpha interferon and of 2-5A synthetase genes is impaired. We also show that beta interferon does not p...

全面介紹

書目詳細資料

發表在:	J Virol
Principais autores:	Deonarain, Raj, Alcamí, Antonio, Alexiou, Maria, Dallman, Margaret J., Gewert, Dirk R., Porter, Andrew C. G.
格式:	Artigo
語言:	Inglês
出版:	American Society for Microbiology (ASM) 2000
主題:	Vaccines and Antiviral Agents
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111842/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10708458/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.7.3404-3409.2000
標簽:	添加標簽 沒有標簽, 成為第一個標記此記錄!