The in vivo antiviral activity of interleukin-12 is mediated by gamma interferon.
The injection of 20 ng of mouse interleukin-12 (IL-12) protects mice from a lethal infection with encephalomyocarditis virus. In vitro, an anti-gamma interferon (anti-IFN-gamma) monoclonal antibody but not an anti-IL-12 monoclonal antibody neutralizes the antiviral activity present in the supernatan...
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| Publicado no: | J Virol |
|---|---|
| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189771/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7494339/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.12.8147-8150.1995 |
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