The in vivo antiviral activity of interleukin-12 is mediated by gamma interferon.

The injection of 20 ng of mouse interleukin-12 (IL-12) protects mice from a lethal infection with encephalomyocarditis virus. In vitro, an anti-gamma interferon (anti-IFN-gamma) monoclonal antibody but not an anti-IL-12 monoclonal antibody neutralizes the antiviral activity present in the supernatan...

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Publicado en:	J Virol
Autores principales:	Ozmen, L, Aguet, M, Trinchieri, G, Garotta, G
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1995
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189771/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7494339/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.12.8147-8150.1995
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