Učitavanje...
Role of mutations G-480 and C-6203 in the attenuation phenotype of Sabin type 1 poliovirus.
Of the 55 point mutations which distinguish the type 1 poliovirus vaccine strain (Sabin 1) from its neurovirulent progenitor (P1/Mahoney), two have been strongly implicated by previous studies as determinants of the attenuation phenotype. A change of an A to a G at position 480, located within the 5...
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| Glavni autori: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
1995
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC189699/ https://ncbi.nlm.nih.gov/pubmed/7494267 |
| Oznake: |
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