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Evaluating stability of attenuated Sabin and two novel type 2 oral poliovirus vaccines in children

Abstract Novel oral poliovirus vaccine type 2 (nOPV2) is being developed to reduce the rare occurrence of disease and outbreaks associated with the genetic instability of the Sabin vaccine strains. Children aged 1 to 5 years were enrolled in two related clinical studies to assess safety, immunogenic...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Rahnuma Wahid, Laina Mercer, Chris Gast, Tirza De Leon, Xavier Sáez-Llorens, Alan Fix, Andrew Macadam, Laura Stephens, Konstantin Chumakov, Saskia L. Smits, Marta Murreddu, Jennifer L. Konopka-Anstadt, M. Steven Oberste, Cara C. Burns, Raul Andino, Novilia Sjafri Bachtiar, Erman Tritama, Ananda S. Bandyopadhyay, Gabriela Aguirre, Ricardo Rüttimann, John O. Konz
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2022-02-01
Schriftenreihe:npj Vaccines
Online-Zugang:https://doi.org/10.1038/s41541-022-00437-5
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