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Correction of sickle cell disease by homologous recombination in embryonic stem cells
Previous studies have demonstrated that sickle cell disease (SCD) can be corrected in mouse models by transduction of hematopoietic stem cells with lentiviral vectors containing antisickling globin genes followed by transplantation of these cells into syngeneic recipients. Although self-inactivating...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society of Hematology
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895869/ https://ncbi.nlm.nih.gov/pubmed/16638928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-02-004812 |
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