Fluctuations of functionally distinct CD8(+) T-cell clonotypes demonstrate flexibility of the HIV-specific TCR repertoire

T-cell receptor (TCR) diversity of virus-specific CD8(+) T cells likely helps prevent escape mutations in chronic viral infections. To understand the dynamics of the virus-specific T cells in more detail, we followed the evolution of the TCR repertoire specific for a dominant HLA-B*08–restricted epi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Meyer-Olson, Dirk, Brady, Kristen W., Bartman, Melissa T., O'Sullivan, Kristin M., Simons, Brenna C., Conrad, Joseph A., Duncan, Coley B., Lorey, Shelly, Siddique, Atif, Draenert, Rika, Addo, Marylyn, Altfeld, Marcus, Rosenberg, Eric, Allen, Todd M., Walker, Bruce D., Kalams, Spyros A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society of Hematology 2006
Pynciau:
Immunobiology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895729/
https://ncbi.nlm.nih.gov/pubmed/16322475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-04-1636
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