Ablation of oncogenic ALK is a viable therapeutic approach for anaplastic large-cell lymphomas

Anaplastic large-cell lymphomas (ALCLs) carry chromosome translocations in which the anaplastic lymphoma kinase (ALK) gene is fused to several partners, most frequently, the NPM1 gene. We have demonstrated that the constitutive activation of ALK fusion proteins results in cellular transformation and...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Piva, Roberto, Chiarle, Roberto, Manazza, Andrea D., Taulli, Riccardo, Simmons, William, Ambrogio, Chiara, D'Escamard, Valentina, Pellegrino, Elisa, Ponzetto, Carola, Palestro, Giorgio, Inghirami, Giorgio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society of Hematology 2006
Gaiak:
Neoplasia
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895619/
https://ncbi.nlm.nih.gov/pubmed/16189272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-05-2125
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