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BH3-only proteins Puma and Bim are rate-limiting for γ-radiation– and glucocorticoid-induced apoptosis of lymphoid cells in vivo
Numerous p53 target genes have been implicated in DNA damage–induced apoptosis signaling, but proapoptotic Bcl-2 (B-cell leukemia 2) family members of the BH3 (Bcl-2 homolog region [BH] 3)–only subgroup appear to play the critical initiating role. In various types of cultured cells, 3 BH3-only prote...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
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© 2005 by The American Society of Hematology
2005
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895232/ https://ncbi.nlm.nih.gov/pubmed/16118324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-04-1595 |
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