Antigen-specific T-cell memory is preserved in children treated for acute lymphoblastic leukemia

Despite profound T-cell immunodeficiency, most patients treated with chemotherapy do not succumb to infection. The basis for residual protective immunity in lymphopenic patients is not known. We prospectively measured T-cell numbers, thymopoiesis, and T-cell memory in 73 children undergoing a 2-year...

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Detalhes bibliográficos
Main Authors: Haining, W. Nicholas, Neuberg, Donna S., Keczkemethy, Heather L., Evans, John W., Rivoli, Stephen, Gelman, Rebecca, Rosenblatt, Howard M., Shearer, William T., Guenaga, Javier, Douek, Daniel C., Silverman, Lewis B., Sallan, Stephen E., Guinan, Eva C., Nadler, Lee M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2005
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895221/
https://ncbi.nlm.nih.gov/pubmed/15920008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-03-1082
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