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Asparaginase-Associated Myelosuppression and Effects on Dosing of Other Chemotherapeutic Agents in Childhood Acute Lymphoblastic Leukemia

Although L-asparaginase (ASP) is associated with several toxicities, its myelosuppressive effect has not been well characterized. On DFCI ALL Consortium Protocol 05-01 for children with newly diagnosed acute lymphoblastic leukemia, the Consolidation phase and the initial portion of the Continuation...

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Detalhes bibliográficos
Publicado no:Pediatr Blood Cancer
Main Authors: Merryman, Reid, Stevenson, Kristen E., Gostic, William J., Neuberg, Donna, O'Brien, Jane, Sallan, Stephen E., Silverman, Lewis B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587903/
https://ncbi.nlm.nih.gov/pubmed/22532399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.24182
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