The relative role of PLCβ and PI3Kγ in platelet activation

Stimulation of platelet G protein–coupled receptors results in the cleavage of phosphatidylinositol 4,5-trisphosphate (PIP(2)) into inositol 1,4,5-trisphosphate and 1,2-diacylglycerol by phospholipase C (PLCβ). It also results in the phosphorylation of PIP(2) by the γ isoform of phosphatidylinositol...

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Detalhes bibliográficos
Main Authors: Lian, Lurong, Wang, Yanfeng, Draznin, Julia, Eslin, Don, Bennett, Joel S., Poncz, Mortimer, Wu, Dianqing, Abrams, Charles S.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2005
Assuntos:
Hemostasis, Thrombosis, and Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895115/
https://ncbi.nlm.nih.gov/pubmed/15705797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-05-2005
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