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Analysis of the spatial and temporal characteristics of platelet-delivered factor VIII–based clots

Normally factor (F) VIII is not expressed in megakaryocytes, but when human FVIII was transgenically expressed in murine megakaryocytes, it was stored in platelet α-granules and released at sites of injury. This platelet FVIII (pFVIII) is effective in correcting hemostasis, even in the presence of c...

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Bibliografske podrobnosti
Main Authors: Neyman, Michael, Gewirtz, Jamie, Poncz, Mortimer
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515146/
https://ncbi.nlm.nih.gov/pubmed/18559671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-04-152959
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