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Insulin-like growth factor-1 regulates platelet activation through PI3-Kα isoform
Platelets release insulin-like growth factor-1 (IGF-1) from α granules upon activation. We have investigated the regulation of IGF-1 in G(i)-dependent pathways leading to Akt activation and the role of IGF-1 in platelet activation. IGF-1 alone failed to induce platelet aggregation, but IGF-1 potenti...
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| Main Authors: | , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
American Society of Hematology
2007
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234779/ https://ncbi.nlm.nih.gov/pubmed/17827385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-03-080804 |
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