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Impaired activation of platelets lacking protein kinase C-θ isoform

Protein kinase C (PKC) isoforms have been implicated in several platelet functional responses, but the contribution of individual isoforms has not been thoroughly evaluated. Novel PKC isoform PKC-θ is activated by glycoprotein VI (GPVI) and protease-activated receptor (PAR) agonists, but not by aden...

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Detalhes bibliográficos
Main Authors: Nagy, Bela, Bhavaraju, Kamala, Getz, Todd, Bynagari, Yamini S., Kim, Soochong, Kunapuli, Satya P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656276/
https://ncbi.nlm.nih.gov/pubmed/19164598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-07-169268
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