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Impaired activation of platelets lacking protein kinase C-θ isoform
Protein kinase C (PKC) isoforms have been implicated in several platelet functional responses, but the contribution of individual isoforms has not been thoroughly evaluated. Novel PKC isoform PKC-θ is activated by glycoprotein VI (GPVI) and protease-activated receptor (PAR) agonists, but not by aden...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Hematology
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2656276/ https://ncbi.nlm.nih.gov/pubmed/19164598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-07-169268 |
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