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Protein Kinase C isoform epsilon (ε) negatively regulates ADP-induced calcium mobilization and thromboxane generation in platelets

OBJECTIVE: Members of Protein Kinase C (PKC) family are shown to positively and negatively regulate platelet activation. Although positive regulatory roles are extensively studied, negative regulatory roles of PKCs are poorly understood. In this study we investigated the mechanism and specific isofo...

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Detalhes bibliográficos
Main Authors: Bynagari-Settipalli, Yamini S, Lakhani, Parth, Jin, Jianguo, Bhavaraju, Kamala, Rico, Mario C., Kim, Soochong, Woulfe, Donna, Kunapuli, Satya P
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331956/
https://ncbi.nlm.nih.gov/pubmed/22362759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.242388
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