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Mast cells contribute to initiation of autoantibody-mediated arthritis via IL-1

Mast cells are immune sentinels that participate in the defense against bacteria and parasites. Resident within the joint, mast cells become activated in human rheumatoid arthritis and are implicated in the pathogenesis of experimental murine synovitis. However, their arthritogenic role remains unde...

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Detalhes bibliográficos
Main Authors: Nigrovic, Peter A., Binstadt, Bryce A., Monach, Paul A., Johnsen, Alyssa, Gurish, Michael, Iwakura, Yoichiro, Benoist, Christophe, Mathis, Diane, Lee, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892913/
https://ncbi.nlm.nih.gov/pubmed/17277081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610852103
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