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Mast cells contribute to initiation of autoantibody-mediated arthritis via IL-1

Mast cells are immune sentinels that participate in the defense against bacteria and parasites. Resident within the joint, mast cells become activated in human rheumatoid arthritis and are implicated in the pathogenesis of experimental murine synovitis. However, their arthritogenic role remains unde...

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Autori principali: Nigrovic, Peter A., Binstadt, Bryce A., Monach, Paul A., Johnsen, Alyssa, Gurish, Michael, Iwakura, Yoichiro, Benoist, Christophe, Mathis, Diane, Lee, David M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892913/
https://ncbi.nlm.nih.gov/pubmed/17277081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610852103
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