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Mast cells contribute to initiation of autoantibody-mediated arthritis via IL-1

Mast cells are immune sentinels that participate in the defense against bacteria and parasites. Resident within the joint, mast cells become activated in human rheumatoid arthritis and are implicated in the pathogenesis of experimental murine synovitis. However, their arthritogenic role remains unde...

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Bibliografiske detaljer
Main Authors: Nigrovic, Peter A., Binstadt, Bryce A., Monach, Paul A., Johnsen, Alyssa, Gurish, Michael, Iwakura, Yoichiro, Benoist, Christophe, Mathis, Diane, Lee, David M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892913/
https://ncbi.nlm.nih.gov/pubmed/17277081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610852103
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