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IL-17-producing T cells can augment autoantibody-induced arthritis

Rheumatoid arthritis is a T lymphocyte-mediated disorder, but the precise nature of T cell involvement remains unclear. In the K/BxN mouse model of inflammatory arthritis, T cells initiate disease by providing help to B cells to produce arthritogenic autoantibodies. Here, we have characterized an ad...

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Detalhes bibliográficos
Main Authors: Jacobs, Jonathan P., Wu, Hsin-Jung, Benoist, Christophe, Mathis, Diane
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799826/
https://ncbi.nlm.nih.gov/pubmed/19955422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912152106
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