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Rituximab specifically depletes short-lived autoreactive plasma cells in a mouse model of inflammatory arthritis

There is increasing appreciation of the important role of B cells in many autoimmune diseases and consequently, increasing interest in treating these disorders through B cell-depletion therapy with rituximab, an anti-CD20 monoclonal antibody. Yet, precisely how this and related drugs exert their the...

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Autori principali: Huang, Haochu, Benoist, Christophe, Mathis, Diane
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842072/
https://ncbi.nlm.nih.gov/pubmed/20176942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001074107
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