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Development of autoimmunity in mice lacking DNA topoisomerase 3β
Mice lacking DNA topoisomerase 3β are predisposed to a shortened lifespan, infertility, and lesions in multiple organs resulting from inflammatory responses. Examination of the immune system of 6- and 52-week-old top3β(−/−) mice revealed no significant aberrations in their central and peripheral tol...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1890479/ https://ncbi.nlm.nih.gov/pubmed/17517607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703587104 |
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