Defective signal transduction in B lymphocytes lacking presenilin proteins

The mammalian presenilin (PS) proteins mediate the posttranslational cleavage of several protein substrates, including amyloid precursor protein, Notch family members, and CD44, but they have also been suggested to function in diverse cellular processes, including calcium-dependent signaling and apo...

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Bibliografiske detaljer
Main Authors: Yagi, Tomohito, Giallourakis, Cosmas, Mohanty, Subhasis, Scheidig, Christina, Shen, Jie, Zheng, Hui, Xavier, Ramnik J., Shaw, Albert C.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242696/
https://ncbi.nlm.nih.gov/pubmed/18195359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707755105
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