Defective signal transduction in B lymphocytes lacking presenilin proteins

The mammalian presenilin (PS) proteins mediate the posttranslational cleavage of several protein substrates, including amyloid precursor protein, Notch family members, and CD44, but they have also been suggested to function in diverse cellular processes, including calcium-dependent signaling and apo...

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Detalhes bibliográficos
Principais autores: Yagi, Tomohito, Giallourakis, Cosmas, Mohanty, Subhasis, Scheidig, Christina, Shen, Jie, Zheng, Hui, Xavier, Ramnik J., Shaw, Albert C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242696/
https://ncbi.nlm.nih.gov/pubmed/18195359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707755105
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