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Function and Dysfunction of Presenilin
The presenilin (PS) genes harbor ~90% of the identified mutations linked to familial forms of Alzheimer’s disease (AD) and the presenilin proteins are essential components of the γ-secretase complex involved in the proteolytic cleavage of type I receptors such as Notch and the amyloid precursor prot...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4000081/ https://ncbi.nlm.nih.gov/pubmed/24107444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000354971 |
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