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Function and Dysfunction of Presenilin

The presenilin (PS) genes harbor ~90% of the identified mutations linked to familial forms of Alzheimer’s disease (AD) and the presenilin proteins are essential components of the γ-secretase complex involved in the proteolytic cleavage of type I receptors such as Notch and the amyloid precursor prot...

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Dades bibliogràfiques
Autor principal: Shen, Jie
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000081/
https://ncbi.nlm.nih.gov/pubmed/24107444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000354971
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