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Presenilins in Synaptic Function and Disease
The presenilin genes harbor approximately 90% of mutations linked to early-onset familial Alzheimer’s disease (FAD), but how these mutations cause the disease is still being debated. Genetic analysis in Drosophila and mice demonstrate that presenilin plays essential roles in synaptic function, learn...
Tallennettuna:
| Päätekijät: | , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2011
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3205282/ https://ncbi.nlm.nih.gov/pubmed/21795114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2011.06.002 |
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