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Aberrant lamination in the cerebral cortex of mouse embryos lacking DNA topoisomerase IIβ

We have examined corticogenesis in mouse embryos lacking DNA topoisomerase IIβ (IIβ) in the brain or in all tissues. The absence of IIβ, a type II DNA topoisomerase normally expressed in postmitotic cells in the developing cortex, severely affects cerebral stratification: no subplate is discernible,...

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Bibliografische gegevens
Hoofdauteurs: Lyu, Yi Lisa, Wang, James C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2003
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC165840/
https://ncbi.nlm.nih.gov/pubmed/12773624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1232376100
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