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Aberrant lamination in the cerebral cortex of mouse embryos lacking DNA topoisomerase IIβ

We have examined corticogenesis in mouse embryos lacking DNA topoisomerase IIβ (IIβ) in the brain or in all tissues. The absence of IIβ, a type II DNA topoisomerase normally expressed in postmitotic cells in the developing cortex, severely affects cerebral stratification: no subplate is discernible,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lyu, Yi Lisa, Wang, James C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2003
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC165840/
https://ncbi.nlm.nih.gov/pubmed/12773624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1232376100
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