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Aberrant lamination in the cerebral cortex of mouse embryos lacking DNA topoisomerase IIβ

We have examined corticogenesis in mouse embryos lacking DNA topoisomerase IIβ (IIβ) in the brain or in all tissues. The absence of IIβ, a type II DNA topoisomerase normally expressed in postmitotic cells in the developing cortex, severely affects cerebral stratification: no subplate is discernible,...

詳細記述

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書誌詳細
主要な著者: Lyu, Yi Lisa, Wang, James C.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC165840/
https://ncbi.nlm.nih.gov/pubmed/12773624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1232376100
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