Aberrant lamination in the cerebral cortex of mouse embryos lacking DNA topoisomerase IIβ
We have examined corticogenesis in mouse embryos lacking DNA topoisomerase IIβ (IIβ) in the brain or in all tissues. The absence of IIβ, a type II DNA topoisomerase normally expressed in postmitotic cells in the developing cortex, severely affects cerebral stratification: no subplate is discernible,...
Sparad:
| I publikationen: | Proc Natl Acad Sci U S A |
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| Huvudupphov: | , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
National Academy of Sciences
2003
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165840/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12773624/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1232376100 |
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